General symptoms of brittle bone disease may be mild or very severe. They include: Broken bones (fractures) Bleeding and easy bruising (frequent nosebleeds or heavy bleeding after an injury) Blue color in the white part of the eyes. Bowing of the legs. Breathing problems. Brittle, discolored teeth. Dec 07, 2018 · Brittle bone disease is caused by a defect in collagen production. Collagen protein is vital in supporting the body. Of the several types of collagen we have, Type I is the most abundant and found in the bones, teeth, ligaments, and eye sclera. Brittle bone disease affects both men and women and people of all races.
Approximately 20 percent of adults with brittle bone disease type 1 develop abnormal sideways or front-to-back curvature of the spine (scoliosis or kyphosis). Additional symptoms associated with brittle bone disease type 1 include loose (hyperextensible) joints, low . Type 4 OI. Type 4 OI is the most variable form of brittle bone disease because its symptoms range from mild to severe. As with type 3 OI, your body produces enough collagen but the quality is poor. Children with type 4 OI are typically born with bowed legs, although the bowing tends to lessen with age.Author: Rose Kivi And Matthew Solan.
Osteogenesis imperfecta, also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily. The severity may be mild to severe. Other symptoms may include a blue tinge to the whites of the eye, short height, loose joints, hearing loss, breathing problems and problems with the teeth. Complications may include cervical artery dissection Causes: Genetic (autosomal dominant, new mutation). Osteogenesis imperfecta, also known as brittle bone disease, is a genetic disorder that causes bones to break easily without cause. The condition affects the body's ability to produce collagen, a protein in the body's connective tissue. There are four types of osteogenesis imperfecta, which vary greatly in how severe they are.
Brittle bone disease in adults Is brittle bone disease curable All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice.